Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25934728 | 0.89 | CRBN (0.48) | CRBNDDB1BRD4CREBBPUCHL1 | |
| SCHEMBL31731123 | 0.83 | DDB1 (0.55) | CRBNDDB1ESR2 | |
| SCHEMBL26100015 | 0.81 | DDB1 (0.48) | CRBNDDB1BRD4CREBBP | |
| SCHEMBL25934619 | 0.80 | CRBN (0.41) | CRBNDDB1ESR2 | |
| SCHEMBL26099800 | 0.80 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL21069325 | 0.80 | PDK4 (0.50) | CRBNDDB1 | |
| SCHEMBL24607909 | 0.79 | CRBN (0.48) | CRBNDDB1 | |
| SCHEMBL29751470 | 0.79 | CRBN (0.48) | CRBNDDB1 | |
| SCHEMBL25934809 | 0.79 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL27221658 | 0.78 | DDB1 (0.55) | CRBNDDB1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |