SCHEMBL25934869

SCHEMBL25934869

CNNC(=O)CNC(=O)c1ncccc1O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.67
EGLN2 Q96KS0 1/20 0.67
TLR7 Q9NYK1 5/20 0.49
L3MBTL1 Q9Y468 3/20 0.46
EGLN1 Q9GZT9 4/20 0.44
VEGFA P15692 1/20 0.44
FLT1 P17948 1/20 0.44
EGLN3 Q9H6Z9 1/20 0.44
RAB9A P51151 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM5B Q9UGL1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
KMT2A Q03164 1/20 0.40
PIM1 P11309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25934714 0.82 FTO (0.74) FTOEGLN2TLR7L3MBTL1EGLN1
SCHEMBL704958 0.80 FTO (1.00) FTOEGLN2TLR7EGLN1VEGFA
SCHEMBL8779266 0.79 EGLN2 (0.70) FTOEGLN2TLR7EGLN1VEGFA
SCHEMBL14122981 0.79 FTO (0.74) FTOEGLN2TLR7L3MBTL1EGLN1
SCHEMBL25934858 0.79 FTO (0.65) FTOEGLN2TLR7EGLN1VEGFA
SCHEMBL23514351 0.79 FTO (0.69) FTOEGLN2TLR7L3MBTL1PIM1
SCHEMBL3724024 0.76 EGLN2 (0.60) FTOEGLN2TLR7L3MBTL1RAB9A
SCHEMBL1921385 0.76 EGLN2 (0.65) FTOEGLN2TLR7L3MBTL1EGLN1
SCHEMBL24405060 0.76 FTO (0.69) FTOEGLN2TLR7L3MBTL1EGLN1
SCHEMBL25934739 0.76 EGLN2 (0.65) FTOEGLN2TLR7EGLN1VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248717-A1 N-(3-HYDROXYPYRIDINE-2-CARBONYL)GLYCINE-BASED ANTITUMOR DRUG SENSITIZER AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248717-A1 N-(3-HYDROXYPYRIDINE-2-CARBONYL)GLYCINE-BASED ANTITUMOR DRUG SENSITIZER AND APPLICATION THEREOF IDO1, PDCD1, IDO2 FTO 1432/4885EGLN2 21/4885TLR7 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.