Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 7/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.40 |
| ▸ | CHRNG | P07510 | 3/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17175237 | 0.80 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL14228092 | 0.80 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL15858573 | 0.80 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL28021585 | 0.79 | GNAI3 (0.57) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL15623802 | 0.78 | GNAI3 (0.60) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL766293 | 0.78 | PAOX (0.44) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL11650885 | 0.77 | PAOX (0.57) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL15871243 | 0.77 | PAOX (0.53) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL21911452 | 0.77 | PAOX (0.57) | PAOXGNAI3GNAO1GNAI1SIRT6 | |
| SCHEMBL8350906 | 0.76 | GNAI3 (0.57) | PAOXGNAI3GNAO1GNAI1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |