Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557646 | 1.00 | BRD4 (0.48) | BRD4CREBBPHDAC1HDAC6NOTUM | |
| SCHEMBL25937707 | 0.87 | BRD4 (0.39) | BRD4CREBBPHDAC1HDAC6PDK1 | |
| SCHEMBL25937726 | 0.84 | DPP8 (0.40) | BRD4CREBBPNOTUMMEN1KMT2A | |
| SCHEMBL3103616 | 0.84 | GRM7 (0.57) | NOTUMCTSLKDM4EMEN1KMT2A | |
| SCHEMBL30557529 | 0.84 | GRM7 (0.57) | NOTUMCTSLKDM4EMEN1KMT2A | |
| SCHEMBL25430562 | 0.83 | HDAC1 (0.55) | BRD4CREBBPHDAC1HDAC6NOTUM | |
| SCHEMBL30557580 | 0.82 | KCNQ2 (0.46) | CTSLMEN1KMT2AKCNQ2ALDH1A1 | |
| SCHEMBL25937545 | 0.82 | KCNQ2 (0.46) | CTSLMEN1KMT2AKCNQ2ALDH1A1 | |
| SCHEMBL4691685 | 0.81 | NOTUM (0.55) | BRD4CREBBPHDAC1HDAC6NOTUM | |
| SCHEMBL31552767 | 0.81 | NOTUM (0.55) | BRD4CREBBPHDAC1HDAC6NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |