Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19888977 | 0.84 | NOTUM (0.65) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL6224256 | 0.82 | NOTUM (0.71) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL27871154 | 0.81 | NOTUM (0.69) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL10664492 | 0.81 | DRD4 (0.57) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL15524285 | 0.80 | NOTUM (0.73) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL7413168 | 0.77 | DRD4 (0.59) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL16907792 | 0.76 | DRD4 (0.67) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL29876158 | 0.76 | DRD4 (0.61) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL16907790 | 0.76 | DRD4 (0.66) | NOTUMKDM4EDRD4L3MBTL1POLB | |
| SCHEMBL10636595 | 0.75 | NOTUM (0.65) | NOTUMKDM4EDRD4L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |