Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876158 | 0.87 | DRD4 (0.61) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL10664492 | 0.85 | DRD4 (0.57) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL10668654 | 0.84 | DRD4 (0.59) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL9629591 | 0.82 | DRD4 (0.57) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL10352868 | 0.81 | NOTUM (0.82) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL10353021 | 0.78 | NOTUM (0.54) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL7417652 | 0.77 | POLB (0.61) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL7408404 | 0.77 | DRD4 (0.49) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL19888977 | 0.77 | NOTUM (0.65) | DRD4NOTUMKDM4EPOLBL3MBTL1 | |
| SCHEMBL9628923 | 0.77 | NOTUM (0.79) | DRD4NOTUMKDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584292-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |