Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31611777 | 1.00 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7828334 | 0.90 | KMT2A (0.73) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26998805 | 0.86 | CYP1A2 (0.67) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9789930 | 0.85 | MAPK1 (0.66) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13994594 | 0.85 | HDAC3 (0.69) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL14679379 | 0.85 | HDAC3 (0.69) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL5592748 | 0.84 | POLB (0.64) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL2014002 | 0.84 | MEN1 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL277376 | 0.84 | HDAC3 (0.64) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL259181 | 0.84 | MEN1 (0.64) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164833-B1 | Quinazolinamide derivatives useful for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | disclosed |
| US-8779159-B2 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8514353-B2 | Color filter and electronic display device | FUJIFILM CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8514353-B2 | Color filter and electronic display device | FUJIFILM CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8501754-B2 | Quinazolinamide derivatives | MERCK PATENT GMBH (DE) | 2013-08-06 | — | — | US | disclosed |
| US-8367282-B2 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367282-B2 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8354208-B2 | Colored curable composition, method for producing color filter, color filter, solid-state image pickup device, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-8354208-B2 | Colored curable composition, method for producing color filter, color filter, solid-state image pickup device, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-8338062-B2 | Colored curable composition, method for producing color filter, color filter, solid-state image pickup device, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| US-20100137585-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009150381-A2 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2009-12-17 | — | — | WO | disclosed |
| US-20080076044-A1 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| US-20070037805-A1 | Fused heteroaryl derivatives | HAYAKAWA MASAHIKO | 2007-02-15 | — | — | US | disclosed |
| US-20070037805-A1 | Fused heteroaryl derivatives | HAYAKAWA MASAHIKO | 2007-02-15 | — | — | US | disclosed |
| US-7173029-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-7173029-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | PIK3CD, PIK3R3, PIK3C2A | HDAC3 162/4885HDAC1 193/4885HDAC2 355/4885 |
| US-20070037805-A1 | Fused heteroaryl derivatives | PIK3CD, PIK3R3, PIK3C2A | HDAC3 162/4885HDAC1 193/4885HDAC2 355/4885 |
| US-20100137585-A1 | FUSED HETEROARYL DERIVATIVES | PIK3CD, PIK3R3, PIK3C2A | HDAC3 162/4885HDAC1 193/4885HDAC2 355/4885 |
| US-20080076044-A1 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | PBRM1, CRY1, MAPT | HDAC3 1598/4885HDAC1 96/4885HDAC2 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.