Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 8/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938833 | 0.99 | HDAC2 (0.38) | HDAC2HDAC1RAD52MAPTPKM | |
| SCHEMBL25938617 | 0.97 | HDAC2 (0.41) | HDAC2HDAC1RAD52MAPTPKM | |
| SCHEMBL25938740 | 0.90 | HDAC1 (0.41) | HDAC2HDAC1RAD52MAPTPKM | |
| SCHEMBL25942676 | 0.86 | TSHR (0.41) | HDAC2HDAC1PKMKMT2AHDAC3 | |
| SCHEMBL25938883 | 0.86 | MAPT (0.53) | HDAC2HDAC1MAPTPKMKMT2A | |
| SCHEMBL25942630 | 0.85 | TSHR (0.43) | HDAC2HDAC1PKMKMT2AHDAC3 | |
| SCHEMBL25942835 | 0.85 | MAPT (0.52) | HDAC2HDAC1MAPTPKMKMT2A | |
| SCHEMBL25942763 | 0.85 | KDM4E (0.43) | HDAC2HDAC1PKMKMT2AKDM4E | |
| SCHEMBL25942831 | 0.84 | ALDH1A1 (0.42) | HDAC2HDAC1PKMKMT2AKDM4E | |
| SCHEMBL25942764 | 0.84 | TSHR (0.41) | HDAC2HDAC1RAD52PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |