Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232845 | 0.83 | TSHR (0.53) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL24267577 | 0.83 | TSHR (0.53) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL25091282 | 0.80 | TSHR (0.50) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL14519190 | 0.78 | TSHR (0.47) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL22644496 | 0.76 | TSHR (0.53) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL5371884 | 0.76 | TSHR (0.53) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL3465276 | 0.76 | TSHR (0.43) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL1812907 | 0.73 | TSHR (0.50) | TSHRALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL16418437 | 0.73 | ALDH1A1 (0.51) | TSHRALDH1A1MAPK1GAACYP2C19 | |
| SCHEMBL13741699 | 0.73 | TSHR (0.54) | TSHRALDH1A1MAPK1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |