Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.33 |
| ▸ | SKP1 | P63208 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30136037 | 1.00 | FFAR4 (0.38) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL25935376 | 0.94 | FFAR4 (0.40) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL25942674 | 0.90 | CKS1B (0.42) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL30965571 | 0.86 | CKS1B (0.42) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL25825537 | 0.86 | CKS1B (0.42) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL31653790 | 0.85 | CKS1B (0.47) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL25935573 | 0.84 | CKS1B (0.43) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL30981123 | 0.83 | FFAR4 (0.38) | FFAR4PRMT5ALOX5APFEN1RORC | |
| SCHEMBL29013211 | 0.83 | FFAR4 (0.39) | FFAR4ALOX5APFEN1CNR1GRM5 | |
| SCHEMBL25419978 | 0.82 | FFAR4 (0.43) | FFAR4PRMT5ALOX5APFEN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242541-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242541-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | PLK1, BUB1B, BUB1 | FFAR4 4754/4885PRMT5 1663/4885ALOX5AP 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.