Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703191 | 0.89 | MAP4K1 (0.39) | MAP4K1 | |
| SCHEMBL24859759 | 0.79 | MAP4K1 (0.71) | MAP4K1 | |
| SCHEMBL25940429 | 0.78 | MAP4K1 (0.46) | MAP4K1KDM4EALDH1A1 | |
| SCHEMBL21684418 | 0.78 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL21703189 | 0.76 | MAP4K1 (0.41) | MAP4K1 | |
| SCHEMBL21684437 | 0.75 | MAP4K1 (0.44) | MAP4K1ALDH1A1RECQL | |
| SCHEMBL31304001 | 0.75 | MAP4K1 (0.44) | MAP4K1ALDH1A1RECQL | |
| SCHEMBL21702990 | 0.74 | MAP4K1 (0.41) | MAP4K1 | |
| SCHEMBL25941865 | 0.74 | MAP4K1 (0.52) | MAP4K1 | |
| SCHEMBL25938622 | 0.72 | MAP4K1 (0.49) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |