Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948777 | 0.91 | RAD52 (0.52) | RAD52ELANEKDM5AKDM5BALOX5 | |
| SCHEMBL25938717 | 0.85 | RAD52 (0.48) | RAD52ELANEKDM5AKDM5BALOX5 | |
| SCHEMBL25942159 | 0.85 | ELANE (0.49) | RAD52ELANEKDM5AKDM5BALOX5 | |
| SCHEMBL25948641 | 0.83 | KDM4E (0.57) | RAD52ELANEALOX5KDM4EMEN1 | |
| SCHEMBL25942157 | 0.80 | ELANE (0.44) | RAD52ELANEKDM5AKDM5BALOX5 | |
| SCHEMBL13954024 | 0.79 | RAD52 (0.55) | RAD52ALOX5KDM4EMEN1KMT2A | |
| SCHEMBL25948664 | 0.79 | RAD52 (0.50) | RAD52ALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL25942228 | 0.77 | RAD52 (0.48) | RAD52ELANEKDM5AKDM5BALOX5 | |
| SCHEMBL25948631 | 0.76 | RAD52 (0.52) | RAD52ALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL25948711 | 0.76 | RAD52 (0.42) | RAD52ALOX5KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |