Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938619 | 0.85 | MAPT (0.41) | RAD52MAPTLMNAGAAKDM4E | |
| SCHEMBL25948641 | 0.80 | KDM4E (0.57) | RAD52LMNAGAAKDM4EALDH1A1 | |
| SCHEMBL25948625 | 0.79 | RAD52 (0.43) | RAD52MAPTGAAALDH1A1TSHR | |
| SCHEMBL25948533 | 0.78 | METAP2 (0.43) | RAD52MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL6488291 | 0.77 | ALDH1A1 (0.58) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL25948777 | 0.76 | RAD52 (0.52) | RAD52MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL25942151 | 0.76 | RAD52 (0.52) | RAD52MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL6688529 | 0.75 | LMNA (0.45) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL8832175 | 0.74 | IDO1 (0.44) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL25948570 | 0.73 | ACSL1 (0.38) | RAD52MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |