Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715321 | 0.88 | ALDH1A1 (0.68) | MAPTALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL11715338 | 0.88 | ALDH1A1 (0.68) | MAPTALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL11723450 | 0.87 | SMN1; SMN2 (0.54) | MAPTALDH1A1LMNAMAPK1POLB | |
| SCHEMBL11723465 | 0.87 | SMN1; SMN2 (0.54) | MAPTALDH1A1LMNAMAPK1POLB | |
| SCHEMBL5040554 | 0.86 | MEN1 (0.55) | ALDH1A1LMNAMAPK1RAB9ANPC1 | |
| SCHEMBL5040549 | 0.86 | MEN1 (0.55) | ALDH1A1LMNAMAPK1RAB9ANPC1 | |
| SCHEMBL1717228 | 0.85 | MAPT (0.51) | MAPTALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL1974848 | 0.85 | MAPT (0.51) | MAPTALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL1717226 | 0.85 | MAPT (0.51) | MAPTALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL2886492 | 0.83 | HSD17B10 (0.55) | MAPTALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |