Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 6/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19050822 | 0.83 | MAP2K1 (0.43) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL14022258 | 0.83 | MAP2K1 (0.49) | MAPK1MAP2K1MAP2K2 | |
| SCHEMBL21306500 | 0.82 | MAP2K2 (0.40) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL23459015 | 0.80 | MAP2K1 (0.38) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL21471500 | 0.80 | MAP2K1 (0.41) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL13672911 | 0.80 | MAP2K1 (0.41) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL15826955 | 0.79 | RAPGEF4 (0.42) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL14263851 | 0.79 | MAP2K2 (0.40) | MEN1KMT2AMAPK1MAP2K1MAP2K2 | |
| SCHEMBL26196763 | 0.79 | MAP2K1 (0.40) | RAPGEF4MEN1KMT2AMAPK1MAP2K1 | |
| SCHEMBL5991001 | 0.79 | MAP2K1 (0.71) | MEN1KMT2AMAPK1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223770-A2 | NOVEL FUSION MOLECULES AND USES THEREOF | Foundation Medicine, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |