Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 14/20 | 0.53 |
| ▸ | MAOB | P27338 | 14/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454654 | 0.98 | MEN1 (0.73) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL4878423 | 0.98 | MEN1 (0.67) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL179913 | 0.91 | MEN1 (0.64) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL11111147 | 0.91 | MEN1 (0.59) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL8284440 | 0.90 | MEN1 (0.69) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL15549968 | 0.83 | MEN1 (1.00) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL20681358 | 0.82 | MEN1 (0.54) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL10388742 | 0.77 | MAOA (0.50) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL10389435 | 0.77 | MEN1 (0.50) | MEN1MAPK1KMT2ANPSR1CDC25B | |
| SCHEMBL10389430 | 0.77 | MEN1 (0.50) | MEN1MAPK1KMT2ANPSR1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |