Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26628339 | 0.84 | CA1 (0.32) | PIK3CDKCNA5 | |
| SCHEMBL4733460 | 0.78 | PIK3CD (0.43) | PIK3CDGABRA1GABRG2GABRB3KCNA5 | |
| SCHEMBL22422351 | 0.74 | FDPS (0.37) | KCNA5FDPS | |
| SCHEMBL13591303 | 0.73 | PIK3CD (0.43) | PIK3CD | |
| SCHEMBL14606836 | 0.73 | PIK3CD (0.43) | PIK3CDGABRA1GABRG2GABRB3KCNA5 | |
| SCHEMBL5948653 | 0.73 | FDPS (0.35) | FDPS | |
| SCHEMBL19216014 | 0.71 | PIK3CD (0.42) | PIK3CDKCNA5 | |
| SCHEMBL22967911 | 0.71 | PIK3CD (0.38) | PIK3CDKCNA5 | |
| SCHEMBL9949840 | 0.70 | MAPT (0.35) | FDPS | |
| SCHEMBL25982999 | 0.70 | FDPS (0.32) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150653-A1 | PROCESS FOR SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2023-08-10 | — | — | WO | disclosed |