Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949561 | 0.89 | CHRM2 (0.44) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL27059386 | 0.89 | CHRM2 (0.44) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL12450345 | 0.84 | PSEN1 (0.40) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL25945745 | 0.80 | MAP4K4 (0.38) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL17631441 | 0.78 | USP2 (0.40) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL17631439 | 0.78 | USP2 (0.40) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL30867754 | 0.78 | SETD7 (0.39) | CHRM2CHRM1CHRM3SETD7MAP4K4 | |
| SCHEMBL19986806 | 0.78 | HSD17B10 (0.44) | MEN1ALDH1A1MAPTKMT2ACHRM2 | |
| SCHEMBL7879359 | 0.77 | MEN1 (0.39) | MEN1ALDH1A1MAPTKMT2ACHRM2 | |
| SCHEMBL7879740 | 0.77 | MEN1 (0.39) | MEN1ALDH1A1MAPTKMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131118-A1 | PROTEIN DEGRADERS DEVELOPED ON BASIS OF BCL-2 FAMILY PROTEIN LIGAND COMPOUNDS AND USE THEREOF | 上海科技大学 | 2023-07-13 | — | — | WO | disclosed |