Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 18/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25945915 | 0.94 | CA1 (0.41) | SCNN1APOLBKDM4EGLAGAA | |
| SCHEMBL12908918 | 0.92 | SCNN1A (0.45) | SCNN1APOLB | |
| SCHEMBL937248 | 0.92 | SCNN1A (0.45) | SCNN1APOLB | |
| SCHEMBL30605326 | 0.92 | CA2 (0.37) | SCNN1APOLB | |
| SCHEMBL25951450 | 0.89 | SCNN1A (0.44) | SCNN1A | |
| SCHEMBL30605341 | 0.88 | SCNN1A (0.43) | SCNN1A | |
| SCHEMBL25935181 | 0.88 | SCNN1A (0.43) | SCNN1A | |
| SCHEMBL25935305 | 0.88 | SCNN1A (0.43) | SCNN1A | |
| SCHEMBL30605310 | 0.86 | SCNN1A (0.38) | SCNN1A | |
| SCHEMBL30605300 | 0.86 | SCNN1A (0.34) | SCNN1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |