Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252603 | 0.86 | RIPK1 (0.63) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL30175221 | 0.84 | RIPK1 (0.61) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL22470881 | 0.84 | RIPK1 (0.61) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17583855 | 0.84 | RIPK1 (0.47) | RIPK1TAAR1HTR2CHRH1SLC6A2 | |
| Hydrochloric Acid SCHEMBL20187811 | 0.83 | RIPK1 (0.46) | RIPK1TAAR1HTR2CHRH1HTR2A | |
| SCHEMBL20472419 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20472415 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29786424 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29786364 | 0.79 | RIPK1 (0.55) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29786590 | 0.79 | RIPK1 (0.59) | RIPK1HTR2CSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |