SCHEMBL2594669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2594226	0.95	EZH2 (0.89)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL2592580	0.95	EZH2 (0.77)	EZH2EZH1EEDSUZ12
	SCHEMBL2592203	0.94	EZH2 (0.76)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL12180175	0.94	EZH2 (0.76)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL2588379	0.93	EZH2 (0.75)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL14717766	0.93	EZH1 (0.75)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL12180173	0.93	EZH2 (0.86)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL29351554	0.92	EZH2 (1.00)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL2595868	0.92	EZH2 (1.00)	EZH2EZH1EEDSUZ12RBBP4
	SCHEMBL2596078	0.91	EZH2 (0.87)	EZH2EZH1EEDSUZ12RBBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.