Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25947259 | 0.82 | SPHK1 (0.44) | HPGDPTGS2CYP3A4SKP2CHRM2 | |
| SCHEMBL2002090 | 0.73 | HPGD (0.61) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27994037 | 0.71 | HPGD (0.58) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL11832671 | 0.70 | NPC1 (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6534660 | 0.69 | HPGD (0.56) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL12846322 | 0.68 | NPC1 (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28161119 | 0.67 | HPGD (0.54) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1187465 | 0.67 | HPGD (0.54) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL16951395 | 0.67 | SPHK1 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2871788 | 0.66 | PTGS2 (0.68) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | disclosed |