Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946426 | 0.96 | ALDH1A1 (0.47) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25947452 | 0.87 | ALDH1A1 (0.60) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25946348 | 0.84 | ALDH1A1 (0.66) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25947796 | 0.83 | ALDH1A1 (0.51) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25947798 | 0.82 | TSHR (0.52) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25941804 | 0.81 | RAD52 (0.41) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25947794 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KMT2ATSHRMAPTPKM | |
| SCHEMBL25946421 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ALOX5KMT2ATSHRMAPT | |
| SCHEMBL25941525 | 0.78 | KDM4E (0.53) | ALDH1A1ALOX5KMT2ATSHRMEN1 | |
| SCHEMBL25946427 | 0.78 | TSHR (0.54) | ALDH1A1ALOX5KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |