Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 11/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25939365 | 0.84 | MAP4K1 (0.54) | ALDH1A1TSHRHSD17B10MAP4K1KDM4E | |
| SCHEMBL25944756 | 0.83 | MAP4K1 (0.57) | ALDH1A1TSHRHSD17B10MAP4K1KDM4E | |
| SCHEMBL25945185 | 0.81 | MAP4K1 (0.58) | ALDH1A1TSHRHSD17B10MAP4K1HDAC3 | |
| SCHEMBL25945823 | 0.80 | MAP4K1 (0.40) | ALDH1A1TSHRHSD17B10MAP4K1KDM4E | |
| SCHEMBL25944422 | 0.78 | MAP4K1 (0.57) | ALDH1A1TSHRHSD17B10MAP4K1HDAC3 | |
| SCHEMBL25945112 | 0.78 | MAP4K1 (0.57) | MAP4K1 | |
| SCHEMBL25938538 | 0.78 | MAP4K1 (0.58) | ALDH1A1TSHRHSD17B10MAP4K1KDM4E | |
| SCHEMBL25944432 | 0.76 | MAP4K1 (0.70) | MAP4K1 | |
| SCHEMBL25940979 | 0.76 | MAP4K1 (0.44) | ALDH1A1TSHRHSD17B10MAP4K1KDM4E | |
| SCHEMBL25944411 | 0.75 | MAP4K1 (0.69) | MAP4K1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |