Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760391 | 0.94 | BTK (0.75) | BTK | |
| SCHEMBL17530745 | 0.92 | BTK (0.86) | BTK | |
| SCHEMBL1392899 | 0.91 | BTK (1.00) | BTK | |
| SCHEMBL10255856 | 0.91 | BTK (0.89) | BTK | |
| SCHEMBL10255445 | 0.91 | BTK (0.80) | BTK | |
| SCHEMBL1394988 | 0.90 | BTK (0.96) | BTK | |
| SCHEMBL1393255 | 0.90 | BTK (0.87) | BTK | |
| SCHEMBL10265729 | 0.89 | BTK (0.86) | BTK | |
| SCHEMBL18777284 | 0.88 | BTK (0.87) | BTK | |
| SCHEMBL20334308 | 0.88 | BTK (0.94) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566869-B1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT INC (US) | 2016-03-02 | — | — | EP | claimed |
| EP-2566869-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | Gilead Connecticut, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140488-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT, INC. (US) | 2011-11-10 | — | — | WO | disclosed |