Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532410 | 0.77 | HTR2C (0.36) | HTR2CCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2902867 | 0.73 | HDAC1 (0.34) | HDAC1HDAC6 | |
| SCHEMBL23176457 | 0.67 | CHRNB2 (0.40) | HTR2CCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2161978 | 0.67 | SKP2 (0.38) | HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL2187720 | 0.66 | AR (0.33) | — | |
| SCHEMBL20599865 | 0.66 | HDAC1 (0.30) | HDAC1HDAC6 | |
| SCHEMBL20599866 | 0.66 | HDAC6 (0.54) | HDAC1HDAC6 | |
| SCHEMBL25145688 | 0.65 | CHRM3 (0.42) | HTR2C | |
| SCHEMBL20757258 | 0.64 | HTR2C (0.66) | HTR2CHTR2BCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL34461094 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |