Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 10/20 | 0.56 |
| ▸ | CDK8 | P49336 | 10/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.44 |
| ▸ | SELE | P16581 | 5/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948367 | 0.89 | CCNC (0.58) | CCNCCDK8PTPN2ICAM1SELE | |
| SCHEMBL25948371 | 0.79 | CDK8 (0.37) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL25948366 | 0.77 | PTPN2 (0.46) | CCNCCDK8PTPN2ICAM1SELE | |
| SCHEMBL20022241 | 0.76 | STING1 (0.66) | PTPN2GPR35STING1 | |
| SCHEMBL28803829 | 0.74 | STING1 (0.62) | PTPN2GPR35STING1BCL2L1 | |
| SCHEMBL25948374 | 0.74 | CDK8 (0.45) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL365991 | 0.74 | MRGPRX4 (0.51) | — | |
| SCHEMBL28860024 | 0.73 | PTPN2 (0.52) | PTPN2GPR35STING1BCL2L1 | |
| SCHEMBL25948369 | 0.72 | KDM4E (0.38) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7053321 | 0.72 | CDK8 (0.66) | CCNCCDK8ICAM1SELEVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |