Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.42 |
| ▸ | SELE | P16581 | 3/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948367 | 0.88 | CCNC (0.58) | PTPN2CCNCCDK8STING1ICAM1 | |
| SCHEMBL29636388 | 0.81 | STING1 (0.61) | PTPN2STING1HDAC1HDAC3HDAC4 | |
| SCHEMBL20022239 | 0.81 | STING1 (0.61) | PTPN2STING1HDAC1HDAC3HDAC4 | |
| SCHEMBL16396262 | 0.78 | PTPN2 (0.55) | PTPN2STING1HDAC1HDAC3HDAC4 | |
| SCHEMBL25948368 | 0.77 | CCNC (0.56) | PTPN2CCNCCDK8STING1ICAM1 | |
| SCHEMBL20563177 | 0.75 | STING1 (0.61) | PTPN2STING1HDAC1HDAC3HDAC4 | |
| SCHEMBL20338887 | 0.75 | PTPN2 (0.53) | PTPN2STING1HDAC1HDAC3HDAC4 | |
| SCHEMBL100069 | 0.75 | MAPT (0.52) | PTPN2HDAC1CLK1DYRK1ADYRK1B | |
| SCHEMBL999671 | 0.75 | HDAC1 (0.56) | PTPN2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL13735896 | 0.72 | PTPN2 (0.59) | PTPN2STING1HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |