Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.30 |
| ▸ | PARP8 | Q8N3A8 | 1/20 | 0.30 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13483977 | 0.79 | PTPN1 (0.35) | PTPN1PTPN2KDM4E | |
| SCHEMBL7947747 | 0.65 | GAA (0.50) | KDM4EMAPT | |
| SCHEMBL13556611 | 0.65 | PTPN2 (0.33) | PTPN1PTPN2 | |
| SCHEMBL25948848 | 0.64 | CDK4 (0.33) | — | |
| SCHEMBL13153126 | 0.64 | GRM5 (0.54) | PTPN1PTPN2KDM4E | |
| SCHEMBL22054405 | 0.64 | PIK3C3 (0.36) | PTPN1PTPN2KDM4E | |
| SCHEMBL25948854 | 0.64 | FNTA (0.38) | ADORA3TNKSPARP1SLC6A3PARP6 | |
| SCHEMBL18747055 | 0.63 | PARP10 (0.61) | TNKSPARP1PARP10TIPARPPARP12 | |
| SCHEMBL19576040 | 0.63 | ADORA2A (0.34) | ADORA3ADORA2AKDM4E | |
| SCHEMBL20448940 | 0.63 | GAA (0.46) | PTPN1PTPN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242533-A9 | SUBSTITUTED FUSED HETEROAROMATIC BICYCLIC COMPOUNDS AS KINASE INHIBITORS AND THE USE THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242533-A9 | SUBSTITUTED FUSED HETEROAROMATIC BICYCLIC COMPOUNDS AS KINASE INHIBITORS AND THE USE THEREOF | ATR, CHEK1, CHEK2 | PTPN1 2003/4885PTPN2 2608/4885ADORA3 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.