Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 9/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949195 | 0.86 | MEN1 (0.66) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL25949199 | 0.84 | RXFP1 (0.65) | KMT2ARXFP1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL24071081 | 0.82 | MAPT (0.67) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL21146669 | 0.82 | RAB9A (0.60) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24070620 | 0.79 | NPC1 (0.59) | RAB9AHTTNPC1MAPTALDH1A1 | |
| SCHEMBL30211942 | 0.79 | NPC1 (0.59) | RAB9AHTTNPC1MAPTALDH1A1 | |
| SCHEMBL21620313 | 0.79 | MEN1 (0.78) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL4253897 | 0.78 | KCNK3 (0.93) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL12764067 | 0.77 | KCNK3 (0.91) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL23367857 | 0.77 | MEN1 (0.69) | MEN1KMT2ARXFP1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | DDR2, DDR1, DDRGK1 | MEN1 3304/4885KMT2A 1757/4885RXFP1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.