Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571701 | 1.00 | RXFP1 (0.43) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL18572103 | 0.89 | RXFP1 (0.54) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL18571944 | 0.87 | RXFP1 (0.39) | RXFP1P2RX1P2RX3P2RX4GPR119 | |
| SCHEMBL23892484 | 0.86 | P2RX1 (0.36) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL18571697 | 0.86 | P2RX1 (0.36) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL25949203 | 0.85 | PI4KA (0.47) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571700 | 0.85 | PI4KA (0.47) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571696 | 0.85 | PI4KA (0.47) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22683096 | 0.82 | RXFP1 (0.49) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL18572012 | 0.82 | RXFP1 (0.49) | RXFP1P2RX1P2RX3P2RX4PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219496-A1 | NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |