SCHEMBL25949546

SCHEMBL25949546

Cc1ccc(C(=O)NC(CN=O)C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
CA2 P00918 9/20 0.46
CA1 P00915 4/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.45
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
UTS2R Q9UKP6 1/20 0.43
GRN P28799 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4682872 0.84 MEN1 (0.53) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL4682874 0.84 MEN1 (0.53) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL12982953 0.82 CA2 (0.65) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL10659467 0.82 MEN1 (0.54) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL12982952 0.82 CA2 (0.65) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL13370243 0.82 CA2 (0.65) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL5867364 0.81 CA2 (0.64) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL18803717 0.79 CA2 (0.57) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL4160513 0.79 CA2 (0.68) MEN1KMT2ASMN1; SMN2ALDH1A1CA2
SCHEMBL29277520 0.79 CA2 (0.62) MEN1KMT2ASMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3708148-B1 MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR POLA CHEM IND INC (JP) 2023-07-19 EP disclosed