Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253758 | 0.98 | MEN1 (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL24177243 | 0.81 | TSHR (0.42) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL14252256 | 0.79 | MEN1 (0.45) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL21300546 | 0.78 | TSHR (0.43) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL14451231 | 0.77 | GRIN1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL14433462 | 0.77 | TSHR (0.41) | TSHRMEN1KMT2AALDH1A1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL1790189 | 0.76 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28929647 | 0.76 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9682044 | 0.76 | SMN1; SMN2 (0.39) | MEN1KMT2AALDH1A1MAPT | |
| Triethylene Glycol SCHEMBL1627441 | 0.74 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137516-A1 | FLAVONOID DIMERS AND THEIR USE | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2011-11-10 | — | — | WO | disclosed |