SCHEMBL9682044

SCHEMBL9682044

CS(=O)(=O)N(CCO)CCO

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.34
CA1 P00915 2/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
MMP1 P03956 2/20 0.31
MMP7 P09237 2/20 0.31
MMP8 P22894 2/20 0.31
MMP12 P39900 2/20 0.31
MMP13 P45452 2/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA14 Q9ULX7 1/20 0.31
APLNR P35414 1/20 0.30
VCAM1 P19320 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16261608 0.90 CA1 (0.50) SMN1; SMN2MAPTCA1KMT2ACA12
SCHEMBL8241145 0.87 SMN1; SMN2 (0.35) SMN1; SMN2MAPTALDH1A1CA1CA12
SCHEMBL14592835 0.84 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL5176138 0.77 MAPT (0.38) SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL2595019 0.76 TSHR (0.43) MAPTALDH1A1MEN1KMT2A
SCHEMBL20173258 0.75
Ethane SCHEMBL4345451 0.74 SMN1; SMN2 (0.38) SMN1; SMN2MAPTCA1NPC1GAA
SCHEMBL796093 0.74
SCHEMBL4437562 0.74 CA1 (0.43) SMN1; SMN2MAPTALDH1A1CA1NPC1
SCHEMBL8654027 0.74 CA1 (0.43) SMN1; SMN2ALDH1A1CA1MMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8870339-B2 Inkjet image forming method FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 US disclosed
US-20110242197-A1 Magenta Dyes and Inks for Use in Ink-Jet Printing Fujifilm Imaging Colorants, Limited (GB) 2011-10-06 US disclosed
US-8017608-B2 5-Phenylthiazole derivatives and their use as p13 kinase inhibitors NOVARTIS AG (CH) 2011-09-13 US disclosed
US-8017608-B2 5-Phenylthiazole derivatives and their use as p13 kinase inhibitors NOVARTIS AG (CH) 2011-09-13 US disclosed
US-20110205290-A1 INKJET IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-08-25 US disclosed
US-20110168053-A1 Weather-Resistant Dye And Use Thereof NINESTAR MANAGEMENT CO., LTD. (CN) 2011-07-14 US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 US disclosed
EP-1608647-B1 5-PHENYLTHIAZOLE DERIVATIVES AND THEIR USE AS P13 KINASE INHIBITORS NOVARTIS AG (CH) 2008-01-09 EP disclosed
US-5095044-A Odorless, discoloration inhibition CIBA-GEIGY CORPORATION (US) 1992-03-10 US disclosed
US-4950795-A PRINTING PLATES, PAPER COATING CIBA-GEIGY CORPORATION (US) 1990-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast NR1H4, NR1D1, NR1D2 SMN1; SMN2 3125/4885MAPT 3802/4885ALDH1A1 529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.