Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | ALPL | P05186 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALPG | P10696 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427306 | 1.00 | KDM4E (0.57) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL30468829 | 1.00 | KDM4E (0.57) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL8247927 | 1.00 | KDM4E (0.57) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL8243518 | 1.00 | KDM4E (0.57) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL14386917 | 0.88 | ESR2 (0.63) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL2595111 | 0.88 | ESR2 (0.63) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL31456143 | 0.88 | ESR2 (0.63) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL2961584 | 0.85 | CYP19A1 (0.54) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL31053988 | 0.85 | CYP19A1 (0.54) | KDM4EBACE1GAAPKMHSD17B10 | |
| SCHEMBL2968452 | 0.85 | CYP19A1 (0.62) | PKMHSD17B10ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253226-B1 | Use of hydroxyflavone derivatives for modifying taste | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2015-07-15 | — | — | EP | claimed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | claimed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | claimed |
| CN-116268354-A | Neotame peculiar smell modifier, atomized essence and aerosol generating device | 深圳昱朋科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2021220208-A1 | IMPRINTED POLYMERS AND METHODS FOR THEIR USE | LIGAR LIMITED PARTNERSHIP (NZ) | 2021-11-04 | — | — | WO | disclosed |
| EP-2948437-B1 | APPROACH FOR SYNTHESIS OF CATECHINS | EPIRIUM BIO INC (US) | 2021-11-03 | — | — | EP | disclosed |
| WO-2018087305-A1 | FUNCTIONAL CHOCOLATE | IMMD SP. Z O.O. (PL) | 2018-05-17 | — | — | WO | disclosed |
| WO-2017208058-A1 | HIGH POLYPHENOLS COCOA POWDER BASED PRODUCTS, USES AND METHODS FOR THE MANUFACTURE THEREOF | CASALUKER S.A. (CO) | 2017-12-07 | — | — | WO | disclosed |
| EP-2433625-B1 | ANTI-OBESITY AGENT COMPRISING COMPOUND CONTAINING BENZOTROPOLONE RING | SUNTORY HOLDINGS LTD (JP) | 2017-09-27 | — | — | EP | disclosed |
| US-9675630-B2 | Compositions and methods of use of A-type procyanidins | MARS, INCORPORATED (US) | 2017-06-13 | — | — | US | disclosed |
| US-9556140-B2 | Approach for synthesis of catechins | SPHAERA PHARMA PVT. LTD. (IN) | 2017-01-31 | — | — | US | disclosed |
| WO-2011140066-A1 | NOVEL PIPERIDINE-FLAVAN ALKALOID COMPOUNDS DERIVED FROM AFRICAN HERB TEA KINKELIBA AS ANTI-DIABETIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| EP-2170317-A1 | TREATMENT OF COPD, GASTRO-ESOPHAGEAL REFLUX DISEASE (GERD), FOOD ALLERGIES AND OTHER GASTROINTESTINAL CONDITIONS AND DISORDERS AMELIORATED BY PROPER HISTAMINE MANAGEMENT USING A COMBINATION OF HISTIDINE DECARBOXYLASE INHIBITORS, LRA DRUGS, ANTI-H1 AND/OR ANTI-H2 DRUGS | Nicolaou, Mike (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20100028469-A1 | Extracts of Cranberry and Methods of Using Thereof | HERBALSCIENCE GROUP, LLC (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2008100539-A1 | TREATMENT OF COPD, GASTRO-ESOPHAGEAL REFLUX DISEASE (GERD), FOOD ALLERGIES AND OTHER GASTROINTESTINAL CONDITIONS AND DISORDERS AMELIORATED BY PROPER HISTAMINE MANAGEMENT USING A COMBINATION OF HISTIDINE DECARBOXYLASE INHIBITORS, LRA DRUGS, ANTI-H1 AND/OR ANTI-H2 DRUGS | NICOLAOU MICHALIS (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | KDM4E 3892/4885BACE1 4004/4885GAA 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.