Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053988 | 1.00 | CYP19A1 (0.54) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL2970150 | 0.90 | CYP19A1 (0.56) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| (2S)-3',4'-Dihydroxy-5,7-Dimethoxyflavan SCHEMBL2968482 | 0.90 | CYP19A1 (0.52) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL31053922 | 0.88 | CYP19A1 (0.50) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL29066388 | 0.86 | ABCG2 (0.59) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL30468829 | 0.85 | KDM4E (0.57) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL18427306 | 0.85 | KDM4E (0.57) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL8243518 | 0.85 | KDM4E (0.57) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL2595124 | 0.85 | KDM4E (0.57) | CYP19A1CLK2EPHX2ALDH1A1MAPT | |
| SCHEMBL8247927 | 0.85 | KDM4E (0.57) | CYP19A1CLK2EPHX2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253226-B1 | Use of hydroxyflavone derivatives for modifying taste | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2015-07-15 | — | — | EP | claimed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | claimed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | claimed |
| EP-2633886-B1 | COMPOUNDS AND MIXTURES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| EP-2253226-B1 | Use of hydroxyflavone derivatives for modifying taste | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | CYP19A1 3419/4885CLK2 2862/4885EPHX2 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.