Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335758 | 0.86 | DHODH (0.55) | POLBSMN1; SMN2PTGER4KMT2AGAA | |
| SCHEMBL2595923 | 0.82 | DHODH (0.52) | POLBGAAL3MBTL1DHODH | |
| SCHEMBL1337018 | 0.82 | DHODH (0.48) | POLBSMN1; SMN2PTGER4KMT2AGAA | |
| SCHEMBL1337640 | 0.76 | BCL2 (0.58) | SMN1; SMN2KMT2ADHODHMAPTBCL2 | |
| SCHEMBL18414391 | 0.74 | BCL2 (0.58) | SMN1; SMN2KMT2ABCL2ALDH1A1MEN1 | |
| SCHEMBL1337628 | 0.73 | AKR1C2 (0.55) | POLBKMT2AGAAL3MBTL1HTT | |
| SCHEMBL15928790 | 0.71 | MEN1 (0.59) | POLBPTGER4KMT2AL3MBTL1DHODH | |
| SCHEMBL1336975 | 0.70 | DHODH (0.79) | GAAL3MBTL1DHODH | |
| SCHEMBL1337577 | 0.70 | DHODH (0.53) | POLBPTGER4KMT2AGAAL3MBTL1 | |
| SCHEMBL17796930 | 0.70 | CHRM3 (0.57) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566847-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | Icozen Therapeutics Pvt. Ltd. (IN) | 2013-03-13 | — | — | EP | claimed |
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | claimed |