SCHEMBL25954875

SCHEMBL25954875

c1ccc(-c2ccc3c(c2)oc2cc(-n4c5ccccc5c5ccc(-c6nc(-c7ccccc7)nc(-c7cccc8c7oc7ccccc78)n6)cc54)ccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
PRKDC P78527 3/20 0.38
PTGER4 P35408 1/20 0.35
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GGPS1 O95749 1/20 0.32
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24217130 1.00 ALOX5 (0.38) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24215903 0.98 ALOX5 (0.39) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL23947893 0.97 ALOX5 (0.37) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24216070 0.96 ALOX5 (0.36) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL21883211 0.96 PRKDC (0.36) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24215894 0.96 ALOX5 (0.34) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL21883292 0.96 ALOX5 (0.40) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24217107 0.96 ALOX5 (0.40) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24215915 0.96 ALOX5 (0.36) ALOX5PRKDCPTGER4MAPTKDM4E
SCHEMBL24216609 0.95 ALOX5 (0.36) ALOX5PRKDCPTGER4MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149667-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-08-10 WO disclosed