Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340371 | 0.90 | PRMT5 (0.46) | PRMT5GPR119MEN1KMT2AHTT | |
| SCHEMBL25338674 | 0.90 | PRMT5 (0.48) | PRMT5GPR119MEN1KMT2AHTT | |
| SCHEMBL24329557 | 0.89 | GPR119 (0.46) | PRMT5GPR119MEN1KMT2ATLR9 | |
| SCHEMBL30568141 | 0.89 | GPR119 (0.46) | PRMT5GPR119MEN1KMT2ATLR9 | |
| SCHEMBL24329305 | 0.89 | PRMT5 (0.46) | PRMT5GPR119MEN1KMT2ATLR9 | |
| SCHEMBL30568153 | 0.81 | GPR119 (0.55) | PRMT5GPR119GLP1R | |
| SCHEMBL25340508 | 0.81 | GPR119 (0.55) | PRMT5GPR119GLP1R | |
| SCHEMBL29555212 | 0.81 | PRMT5 (0.49) | PRMT5GPR119MEN1KMT2AHTT | |
| SCHEMBL24329756 | 0.81 | PRMT5 (0.49) | PRMT5GPR119MEN1KMT2AHTT | |
| SCHEMBL24330447 | 0.81 | PRMT5 (0.46) | PRMT5GPR119ALDH1A1MAPTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |