Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064407 | 0.84 | FLT3 (0.36) | TDP1KDM4EFLT3GABRA1GABRB2 | |
| SCHEMBL24630603 | 0.80 | GABRA1 (0.48) | TDP1KDM4EFLT3GABRA1GABRB2 | |
| SCHEMBL15861173 | 0.80 | CA1 (0.43) | TDP1CA1CA2KDM4EHTT | |
| SCHEMBL25955820 | 0.79 | TSHR (0.42) | TDP1CA1CA2KDM4EHTT | |
| SCHEMBL26715054 | 0.78 | MEN1 (0.41) | TDP1KDM4EFLT3GABRA1GABRB2 | |
| SCHEMBL25962670 | 0.77 | CYP1A2 (0.42) | TDP1KDM4EFLT3GABRA1GABRB2 | |
| SCHEMBL25955472 | 0.76 | GABRA1 (0.39) | TDP1KDM4EFLT3GABRA1GABRB2 | |
| SCHEMBL25996460 | 0.76 | ESR2 (0.40) | CA1CA2KDM4EHTTESR2 | |
| SCHEMBL24791895 | 0.76 | ESR1 (0.47) | TDP1KDM4EFLT3HTTGABRA1 | |
| SCHEMBL26173903 | 0.76 | ESR2 (0.38) | TDP1CA1CA2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |