Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25956364 | 0.83 | TRPV1 (0.45) | EPHX2PIK3CATRPV1EGFR | |
| SCHEMBL25956232 | 0.82 | KDM4E (0.43) | EPHX2TRPV1EGFR | |
| SCHEMBL25974055 | 0.82 | EPHX2 (0.46) | EPHX2TRPV1 | |
| SCHEMBL25974136 | 0.77 | EPHX2 (0.48) | EPHX2TRPV1 | |
| SCHEMBL30482552 | 0.77 | EGFR (0.47) | EPHX2TRPV1EGFR | |
| SCHEMBL26202876 | 0.77 | EGFR (0.47) | EPHX2TRPV1EGFR | |
| SCHEMBL25428478 | 0.74 | TRPV1 (0.42) | EPHX2TRPV1 | |
| SCHEMBL25339314 | 0.74 | TRPV1 (0.46) | EPHX2TRPV1EGFR | |
| SCHEMBL25338503 | 0.71 | TRPV1 (0.53) | TRPV1EGFR | |
| SCHEMBL25341133 | 0.70 | MKNK1 (0.51) | EPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |