Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958397 | 0.85 | CRBN (0.53) | DDB1CRBN | |
| SCHEMBL24608128 | 0.79 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL29751502 | 0.79 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL26782478 | 0.77 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL31134628 | 0.76 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL21997628 | 0.74 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL23832603 | 0.74 | DDB1 (0.45) | DDB1CRBN | |
| SCHEMBL29347152 | 0.73 | HTR4 (0.32) | DDB1CRBN | |
| Trifluoroacetic Acid SCHEMBL30392561 | 0.73 | DDB1 (0.46) | DDB1CRBN | |
| SCHEMBL25961447 | 0.72 | DDB1 (0.51) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |