Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758273 | 0.87 | GAA (0.44) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL29027783 | 0.84 | GAA (0.41) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL21002088 | 0.82 | GAA (0.49) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL27329777 | 0.77 | GAA (0.48) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL30758185 | 0.77 | GAA (0.40) | GAACYP2C19ALDH1A1KMT2A | |
| SCHEMBL20488945 | 0.76 | GAA (0.44) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL31281723 | 0.76 | GAA (0.44) | GAACYP4F2CYP4A11RETCYP2C19 | |
| SCHEMBL25958665 | 0.76 | GAA (0.39) | GAACYP4F2CYP4A11 | |
| SCHEMBL19255898 | 0.76 | GAA (0.39) | GAACYP4F2CYP4A11 | |
| SCHEMBL1475947 | 0.74 | ALDH1A1 (0.43) | GAACYP4F2CYP4A11RETCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250079-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250079-A1 | SMALL MOLECULE MODULATORS OF IL-17 | IL17A, IL2, IL23R | GAA 920/4885CYP4F2 2305/4885CYP4A11 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.