Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593210 | 0.83 | GPR119 (0.70) | GPR119 | |
| SCHEMBL2593204 | 0.83 | GPR119 (0.70) | GPR119 | |
| SCHEMBL12183705 | 0.83 | GPR119 (0.70) | GPR119 | |
| SCHEMBL2589587 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2595902 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2589585 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12184345 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12183709 | 0.78 | GPR119 (0.85) | GPR119 | |
| SCHEMBL12183777 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL14739388 | 0.77 | GPR119 (0.75) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566862-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | Bristol-Myers Squibb Company (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140161-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |