Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547228 | 0.81 | TLR8 (0.36) | TLR7MCHR1NCF1 | |
| SCHEMBL20547479 | 0.81 | TLR7 (0.40) | TLR7MCHR1NCF1 | |
| SCHEMBL21712374 | 0.81 | TLR8 (0.45) | TLR7MCHR1HTTNCF1 | |
| SCHEMBL30662199 | 0.81 | TLR8 (0.45) | TLR7MCHR1HTTNCF1 | |
| Hydrochloric Acid SCHEMBL21712391 | 0.81 | TLR8 (0.36) | TLR7MCHR1NCF1 | |
| Hydrochloric Acid SCHEMBL30612948 | 0.81 | TLR8 (0.36) | TLR7MCHR1NCF1 | |
| SCHEMBL30662172 | 0.81 | NCF1 (0.39) | TLR7NCF1 | |
| SCHEMBL21712361 | 0.81 | NCF1 (0.39) | TLR7NCF1 | |
| SCHEMBL30662177 | 0.80 | TLR7 (0.53) | TLR7KDM4EALDH1A1HPGDMTNR1A | |
| SCHEMBL21712415 | 0.80 | TLR7 (0.53) | TLR7KDM4EALDH1A1HPGDMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |