⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18339382 | 0.80 | — | — | |
| SCHEMBL24536561 | 0.77 | USP2 (0.32) | — | |
| SCHEMBL1139876 | 0.74 | OPRM1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL4835639 | 0.72 | OPRM1 (0.43) | — | |
| SCHEMBL23339673 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL16573822 | 0.69 | — | — | |
| SCHEMBL22307714 | 0.67 | — | — | |
| SCHEMBL20334952 | 0.67 | — | — | |
| SCHEMBL24795248 | 0.65 | — | — | |
| SCHEMBL696010 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |