Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148619 | 0.87 | PIK3CD (0.56) | PIK3CDKDM4ECYP1A2MAPK1TSHR | |
| SCHEMBL14894947 | 0.84 | HRH3 (0.35) | PIK3CDHRH3CHRM2CHRM4CHRM1 | |
| SCHEMBL1018851 | 0.82 | ALDH1A1 (0.41) | HRH3KDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL28256928 | 0.81 | HRH3 (0.34) | PIK3CDHRH3CHRM2CHRM4CHRM1 | |
| SCHEMBL24755750 | 0.80 | PIK3CD (0.44) | PIK3CD | |
| Water SCHEMBL15361516 | 0.80 | ALDH1A1 (0.40) | HRH3CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL15361701 | 0.80 | ALDH1A1 (0.40) | HRH3KDM4EALDH1A1TDP1MEN1 | |
| Bromide SCHEMBL15361748 | 0.80 | ALDH1A1 (0.40) | HRH3CHRM2CHRM4CHRM1CHRM3 | |
| Fluoride SCHEMBL15361776 | 0.80 | ALDH1A1 (0.40) | HRH3CHRM2CHRM4CHRM1CHRM3 | |
| Iodide SCHEMBL15361734 | 0.80 | ALDH1A1 (0.40) | HRH3CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |