Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086241 | 0.84 | PIM1 (0.44) | MAPK14PARP1KDM4EPOLBGAA | |
| SCHEMBL30825422 | 0.84 | PIM1 (0.44) | MAPK14PARP1KDM4EPOLBGAA | |
| SCHEMBL21200206 | 0.83 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL29866826 | 0.80 | MAPK14 (0.42) | MAPK14PARP1CA12CA1CA2 | |
| SCHEMBL21200136 | 0.80 | MAPK14 (0.42) | MAPK14PARP1CA12CA1CA2 | |
| SCHEMBL30450993 | 0.74 | CLK4 (0.46) | PARP1CA12CA1CA2CA7 | |
| SCHEMBL19474641 | 0.74 | CLK4 (0.46) | PARP1CA12CA1CA2CA7 | |
| SCHEMBL22990372 | 0.72 | PARP10 (0.47) | PARP1CA12CA1CA2CA7 | |
| SCHEMBL24001517 | 0.72 | PIK3CD (0.47) | PARP1KDM4EPOLBGAA | |
| SCHEMBL24001571 | 0.71 | MAPK14 (0.34) | MAPK14PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219504-A1 | MACROCYCLIC TLR7 AGONIST, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Visonpharma Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |