Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | MST1R | Q04912 | 1/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19474641 | 1.00 | CLK4 (0.46) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL31098601 | 0.88 | SMYD3 (0.53) | CLK4CASP3NTRK1PRKACAFLT3 | |
| SCHEMBL4611577 | 0.88 | SMYD3 (0.53) | CLK4CASP3NTRK1PRKACAFLT3 | |
| SCHEMBL14395236 | 0.85 | PARP10 (0.56) | CASP3PRKACACA12CA9CA1 | |
| SCHEMBL20446302 | 0.82 | NPC1 (0.53) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL5879567 | 0.80 | TDP2 (0.61) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL27491542 | 0.79 | PRF1 (0.55) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL28367558 | 0.78 | CLK4 (0.46) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL29873105 | 0.78 | CLK4 (0.49) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL24348699 | 0.77 | CA12 (0.44) | CLK4DYRK1BNTRK2TYRO3FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |