Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.43 |
| ▸ | MAOA | P21397 | 14/20 | 0.43 |
| ▸ | MAOB | P27338 | 14/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216596 | 0.78 | KDM1A (0.48) | KDM1AMAOAMAOBCHRM2CHRM4 | |
| SCHEMBL29002923 | 0.72 | KDM1A (0.46) | KDM1AMAOAMAOBALDH1A1GLA | |
| SCHEMBL28438231 | 0.71 | KDM1A (0.46) | KDM1AMAOAMAOB | |
| SCHEMBL27517581 | 0.70 | KDM1A (0.40) | KDM1AMAOAMAOBCHRM2CHRM4 | |
| SCHEMBL9100498 | 0.69 | CHRM2 (0.50) | KDM1AMAOAMAOBCHRM2CHRM4 | |
| SCHEMBL4331068 | 0.68 | KDM1A (0.67) | KDM1AMAOAMAOB | |
| SCHEMBL28428139 | 0.68 | KDM1A (0.46) | KDM1AMAOAMAOB | |
| SCHEMBL8747222 | 0.67 | KDM1A (0.54) | KDM1AMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL11017865 | 0.66 | KDM1A (0.64) | KDM1AMAOAMAOB | |
| SCHEMBL27615490 | 0.66 | KDM1A (0.52) | KDM1AMAOAMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | KRAS, HRAS, MTOR | KDM1A 3134/4885MAOA 4597/4885MAOB 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.